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Moreover, IL1R1 expression was also increased upon T treatment, suggesting enhanced inflammatory signaling within the prostatic tissue, while PWE co-treatment restored protein levels similarly to untreated group (Figure 6F)

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The pharmaceutical agents also showed a reduction of clinical symptoms, improvement of PFT values, and health-related quality of life as well as systemic and lung inflammation and oxidative stress in patients suffering from various chronic lung diseases including SM-induced pulmonary complications

Given that FRG2 is located at about 100 kilobases away from telomeres, the above finding suggests that due to shrinking telomeres,